home *** CD-ROM | disk | FTP | other *** search
- $Unique_ID{BRK03619}
- $Pretitle{}
- $Title{Condyloma}
- $Subject{Condyloma Venereal Wart Genital Wart Condyloma Acuminatum Condyloma
- Latum Condyloma Acuminatum, Giant Busche-Lowenstein Tumor Common Warts Bowen's
- Disease Herpes Simplex Squamous Cell Carcinoma}
- $Volume{}
- $Log{}
-
- Copyright (C) 1990 National Organization for Rare Disorders, Inc.
-
- 754:
- Condyloma
-
- ** IMPORTANT **
- It is possible that the main title of the article (Condyloma) is not the
- name you expected. Please check the SYNONYM listing to find the alternate
- names and disorder subdivisions covered by this article.
-
- Synonyms
-
- Venereal Wart
- Genital Wart
- Condyloma Acuminatum
-
- Disorder Subdivision:
-
- Condyloma Latum
- Condyloma Acuminatum, Giant (also known as Busche-Lowenstein Tumor)
-
- Information on the following diseases can be found in the Related
- Disorders section of this report:
-
- Common Warts
- Bowen's Disease
- Herpes Simplex
- Squamous Cell Carcinoma
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section of this report.
-
- Condyloma is a wart. It is caused by the human papilloma virus (HPV)
- and usually transmitted by direct sexual contact. These warts can be found
- on the genitals, mucous membranes of the mouth, near the anus, or in the
- rectum.
-
- Symptoms
-
- Condyloma is a common infectious venereal disease that is characterized by
- small, soft, moist, pink or red elevations on the skin or mucous membranes
- (warts). These warts are caused by direct contact with the papilloma virus
- (human papilloma virus (HPV), either type 1, 2, 6, or 11). They have an
- incubation period of 1 to 6 months. The warts are not painful but they can
- spread rapidly on the genitals, mucous membranes, around the anus, and in the
- rectum. Occasionally there may be a single wart, but most often they cluster
- together, taking on a cauliflower-like appearance.
-
- In females, condylomas can be found on the walls of the vagina or cervix,
- on the area between the vulva and anus (perineum), or in the rectum.
- Pregnancy or a chronic vaginal discharge can cause these warts to grow and
- spread more rapidly. Regular examinations by a gynecologist, that includes a
- Pap Test, are important for women who have had venereal warts. An increased
- number of cases of cervical cancer in women with Condyloma has shown a
- distinct connection between cancer and the HPV virus.
-
- Men who have been infected with the human papilloma virus may have
- Condyloma warts around the foreskin and/or shaft of the penis, around the
- anus or in the rectum. Occasionally, they may involve the urethra which is
- the tube that extends through the penis into the bladder allowing urination.
-
- Condyloma Latum is a type of venereal wart that is a sign of secondary
- Syphilis in women. It is a highly contagious disease and is characterized by
- broad, flat, irregular-shaped patches on the vulva or anus.
-
- Giant Condyloma Acuminatum, also known as Buschke-Lowenstein tumor, is a
- form of Condyloma that can affect women but is more common in uncircumcised
- males. Although these warts appear most often on the penis, they may occur
- on the mucous membranes of the mouth, rectum, vulva or the area between the
- vagina and rectum in women. They can spread rapidly, causing the foreskin on
- the head of the penis to draw together (phimosis). Circumcision, which is a
- surgical removal of the foreskin, would help in preventing this form of
- Condylomata in males.
-
- Causes
-
- Condyloma is a common infectious venereal disease that is caused by the human
- papilloma virus (HPV). It is transmitted by direct sexual contact.
-
- Affected Population
-
- Condyloma is an infectious disease that affects males and females equally.
- Sexual practices, multiple sexual partners, poor hygiene, and an early onset
- of sexual activity have all been implicated in an increased susceptibility to
- this virus. Pregnant women are more prone to this disease, and if not
- adequately treated can transmit the virus to the baby at the time of
- delivery. Incidence of rectal and anal warts are more commonly found among
- homosexual males.
-
- Related Disorders
-
- Symptoms of the following disorders can be similar to those of Condyloma.
- Comparisons may be useful for a differential diagnosis.
-
- Bowen's Disease is a precancerous, slow growing skin malignancy. It is
- characterized by irregularly shaped, pinkish or brownish raised areas of skin
- (papules). This skin disease can occur on any part of the body, in the
- mucous membranes or on the genitals. (For more information on this disorder,
- choose "Bowen" as your search term in the Rare Disease Database.)
-
- Common Warts or verruca are small hard raised growths on the surface of
- the skin. These growths are caused by a virus and can appear on any part of
- the body. Warts can vary from normal skin color to a dark brown-black and
- occur most often on the fingers, elbows, and knees. Less frequently they can
- occur on the face and around the edges of the nails.
-
- Herpes Simplex is a common recurrent infection by the herpes simplex
- virus. It is characterized by clusters of small blisters filled with clear
- fluid on slightly red bases. These blisters can appear on the skin, mucous
- membranes and the genital area. The virus is transmitted by direct contact
- with the lesions, sometimes during sexual contact.
-
- Squamous Cell Carcinomas are common skin cancers usually appearing on the
- sun exposed areas of the skin. However they may occur anywhere on the body,
- including the genitals. The lesions begin as a small red elevation or patch
- with a scaly or crusted surface. They may become nodular, sometimes with a
- warty surface. In some, the bulk of the lesion may lie below the level of
- the surrounding tissue. A biopsy is essential to diagnose this disorder.
-
- Therapies: Standard
-
- Since Condyloma is a sexually transmitted disease, both partners should be
- examined and treated. Treatment of Condyloma consists of topical medications
- such as podophyllin or trichloroacetic acids. This treatment may need to be
- repeated to assure complete removal of the warts. Genital warts may also be
- treated under local or general anesthesia by an exposure to extreme cold
- (cryosurgery), or by cauterizing the wart with heat from an electric current
- (electrocauterization) or laser therapy. Surgical removal may be necessary
- for the more extensive cases of this disease. Condylomas are difficult to
- treat, relapses are frequent, and several treatments are often necessary.
- Circumcision may help to prevent a recurrence of this disease in men.
- Condoms, used correctly, can give some protection and help to avoid re-
- infection from this and other sexually transmitted diseases.
-
- Those people who have been diagnosed with the papilloma virus (types 6,
- 11, 16, and 18), and their sexual partners, should be followed closely by
- their physicians. This is due to the fact that certain forms of cancer have
- occurred after a history of genital warts.
-
- Therapies: Investigational
-
- The orphan drugs Interferon Alpha-2B and Interferon-NL are being tested as
- treatments for the human papillomavirus in those patients with recurrent
- respiratory (Laryngeal) papillomatosis. For more information on the Orphan
- Drug Interferon-Alpha-2B, physicians can contact Schering Corp., 2000
- Galloping Hill Road, Kenilworth, NJ 07033. (For more information on the
- Orphan Drug Interferon-NL, physician can contact Burroughs Wellcome, 3030
- Cornwallis Road, Research Triangle Park, NC 27709.
-
- This disease entry is based upon medical information available through
- July 1990. Since NORD's resources are limited, it is not possible to keep
- every entry in the Rare Disease Database completely current and accurate.
- Please check with the agencies listed in the Resources section for the most
- current information about this disorder.
-
- Resources
-
- For more information on Condyloma, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- American Social Health Association
- 100 Capitola Dr., Suite 200
- Research Triangle Park, NC 27713
- (919) 361-8400
-
- National Sexully Transmitted Diseases Hotline
- (800) 227-8922
-
- Council for Sex Education and Information
- 444 Lincoln Blvd., Suite 107
- Venice, CA 90291
-
- NIH/National Institute of Allergy and Infectious Diseases (NIAID)
- 9000 Rockville Pike
- Bethesda, MD 20892
- (301) 496-5717
-
- Centers for Disease Control (CDC)
- 1600 Clifton Road, NE
- Atlanta, GA 30333
- (404) 639-3534
-
- References
-
- THE MERCK MANUAL, Volume 2, 15th Ed.: Robert Berkow, M.D., ed.-in-chief;
- Merck Sharp & Dohme Laboratories., 1988. Pp. 250.
-
- TEXTBOOK OF MEDICINE, 18th Ed.: James B. Wyngaarden, M.D. et al.; ed.-in-
- chief; W.B. Saunders Co., 1988. Pp. 2324.
-
- CONDYLOMATA ACUMINATA (VENEREAL WARTS). J. Enterline, et al.; NURSE PRACT
- (April 1989, issue 14 (4)). Pp. 8-16.
-
- INTERFERONS IN THE TREATMENT OF GENITAL HUMAN PAPILLOMAVIRUS INFECTIONS.
- P. Weck, et al.; AM J MED (August 29, 1988, issue 85(2)). Pp. 159-164.
-
- HUMAN PAPILLOMAVIRUS TYPING OF PENILE CONDYLOMA. W. O'Brien, et al.; J
- UROL (April 1989, issue 141(4)). Pp. 863-865.
-
- CERVICAL DYSPLASIA AND HUMAN PAPILLOMAVIRUS. J. Carmichael, et al.; AM J
- OBSTET GYNECOL (April 1989, issue 160(4)). Pp. 916-918.
-
- PATIENT APPLIED PODOFILOX FOR TREATMENT OF GENITAL WARTS. K. Beutner, et
- al.; LANCET (April 1989, issue 1(8642)). Pp. 831-834.
-
- HUMAN PAPILLOMAVIRUS INFECTION: A POTENTIALLY CARCINOGENIC SEXUALLY
- TRANSMITTED DISEASE (CONDYLOMATA, GENITAL WARTS). V. Lucas; NURS CLIN NORTH
- AM (December 1988, issue 23 (4)). Pp. 917-935.
-
-